DES (1-3) IGF-1 1mg – Int | Powerful Site-Enhancement Peptide for Growth

DES (1-3) IGF-1 1mg – Int | Rapid-Acting Peptide for Extreme Muscle Growth

DES (1-3) IGF-1 1mg – Int is an ultra-potent, short-chain analog of Insulin-Like Growth Factor 1 (IGF-1), engineered to deliver targeted, site-specific muscle growth. This international-grade peptide is prized by bodybuilders, performance athletes, and biohackers for its enhanced receptor binding, localized anabolic effects, and accelerated tissue repair.

Unlike standard IGF-1, DES (1-3) is up to 10x more powerful, bypasses typical IGF-binding proteins, and acts directly at the muscle injection site, making it ideal for spot-enhancement and growth-phase cycles.


🧪 Product Overview

  • Peptide: DES (1-3) IGF-1
  • Form: Lyophilized (freeze-dried) peptide
  • Concentration: 1mg per vial
  • Administration: Intramuscular (IM) or subcutaneous (SubQ), ideally near the muscle group trained
  • Source: International (Int)
  • Storage: Refrigerate after reconstitution

⚙️ How DES (1-3) IGF-1 Works

DES (1-3) is a shortened IGF-1 peptide with enhanced ability to bind IGF-1 receptors, especially in damaged or growing muscle tissue. Unlike IGF-1 LR3, DES acts immediately and locally—triggering hyperplasia (new muscle cell formation) and enhanced cell proliferation post-training.


💪 Key Benefits

  • 🚀 Accelerated muscle growth & hypertrophy
  • 📈 Targeted anabolic effects when injected intramuscularly
  • 🛠️ Rapid repair of muscle fibers and soft tissue
  • 🔥 Ideal for site-specific muscle enhancement
  • ⏱️ Fast-acting with short half-life for acute response
  • 💉 Minimal systemic effect—perfect for localized gains

📋 Suggested Usage Protocol

GoalDosageTimingCycle Length
Muscle growth (localized)50–100mcgPost-workout, site injection4–6 weeks
Muscle recovery40–80mcg1–2x per day (injury site)2–4 weeks
Stack support50mcgWith IGF-1 LR3 or GH4–6 weeks
  • Reconstitute with bacteriostatic water (1–2mL)
  • Inject directly into muscle worked (bi-lateral dosing optional)
  • Use fine insulin syringe (29–31G) for precision

⚠️ Due to its short half-life (~30 minutes), timing around workouts is critical for max results.


Side Effects & Considerations

  • Injection-site irritation (mild)
  • Hypoglycemia (rare, but possible with high doses)
  • Desensitization if overused
  • Not recommended for long-term daily use without cycling

Cycle responsibly and consider 2 weeks on / 2 weeks off or combine with IGF-1 LR3 for sustained effects.


🔗 Best Stack Combinations

  • DES (1-3) + IGF-1 LR3 – short- and long-acting synergy
  • DES + Growth Hormone (GH) – amplified muscle hyperplasia
  • DES + BPC-157 or TB-500 – for injury repair and muscle regeneration
  • DES + Androgens (e.g., Testosterone, Tren) – max muscle response

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