PNC-27 – 5mg/vial – Deus Medical

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🧬 What Is PNC-27?

PNC-27 is a synthetic peptide engineered to target and destroy cancerous cells while leaving healthy cells unharmed. It was developed by fusing a p53 tumor-suppressor sequence with a membrane-disrupting peptide, enabling it to penetrate cancer cells and induce rapid necrosis.

Deus Medical’s PNC-27 (5mg/vial) delivers a high-purity research-grade version of this cutting-edge molecule, widely studied for its selective cytotoxicity against malignant tumors.

⚠️ For research use only. Not approved for human consumption or medical treatment.

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🧪 How PNC-27 Works

PNC-27 combines a cell-penetrating peptide with a segment of the p53 protein, which is commonly mutated or dysfunctional in many cancers. The peptide targets the HDM-2 (Human Double Minute-2) protein, often overexpressed on cancer cell membranes. Upon binding:

• It forms membrane pores
• Induces cancer cell lysis (rupture)
• Spares noncancerous, healthy cells

This targeted mechanism has made it an intriguing candidate in experimental oncology.

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🔬 Potential Research Benefits

🧫 Selectively kills cancer cells (shown in vitro and in vivo studies)
🧬 Targets tumors with overexpressed HDM-2 protein
❌ Minimal to no toxicity in normal cells
⚙️ Supports study of tumor necrosis mechanisms
🧠 Research on glioblastoma, melanoma, breast, and pancreatic cancer

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💉 Dosage & Handling (Research Use Only)

• Typical Research Concentration: Variable depending on cell line or animal model
• Route: In vitro application or injection in lab studies
• Reconstitution: Use sterile bacteriostatic water or acetic acid per protocol
• Storage: Refrigerate between 2–8°C; do not freeze reconstituted solution

Researchers must follow institutional guidelines and protocols for peptide use in preclinical models.

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⚠️ Safety Information

PNC-27 is for laboratory research use only.

• Not for human use, injection, or consumption
• Handle with standard PPE in lab settings
• Dispose of per institutional biosafety protocols