Tauroursodeoxycholic (90 tabs)

Mechanism of medicine action:

TUDCA exerts its effects primarily through its action on cellular stress pathways. It helps prevent apoptosis (cell death) in liver and neuronal cells by stabilizing the endoplasmic reticulum, promoting protein folding, and reducing accumulation of misfolded proteins. Furthermore, TUDCA alters bile acid composition and promotes choleresis, thereby enhancing bile flow and hepatic function.

Indications:

TUDCA is indicated for the management of liver-related conditions such as cholestasis, non-alcoholic fatty liver disease (NAFLD), and liver fibrosis. It has also been studied for potential neuroprotective effects in conditions such as Huntington’s disease and other neurodegenerative disorders, though more research is warranted in these areas.

Contraindications:

TUDCA should be used with caution in individuals with known hypersensitivity to bile acids or taurine. Additionally, contraindications may include severe hepatic dysfunction or acute liver failure, as its role is primarily supportive in hepatic health.

Precautions:

Patients taking TUDCA should be monitored for any signs of adverse reactions, especially in individuals with existing liver conditions. It is also advisable to conduct liver function tests periodically to assess tolerance and effectiveness during treatment.

Drug interactions:

TUDCA may interact with other medications metabolized through hepatic pathways. There is potential for interactions with medications affecting bile acid transport or liver enzyme inducers/inhibitors. Consultation with a healthcare provider is essential when combining TUDCA with other therapies.

Dosage:

The typical dosage of TUDCA for adults ranges from 250 mg to 1500 mg daily, divided into multiple doses. However, the specific dosage may vary based on the condition being treated and should be determined by a healthcare professional.

Storage:

Store in a dark, dry place, at room temperature. Keep out of reach of children.

Regulatory Compliance Statements:

• This product complies with relevant regulatory guidelines.
• Certified under Good Manufacturing Practices (GMP).

Safety Information:

• Overdose Instructions: In case of overdose, seek immediate medical attention.
• Adverse Reactions: Report any adverse reactions to your healthcare provider.